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Kallikrein 7 Protein (KLK7) (His tag)

KLK7 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320700
发货至: 中国
  • 抗原 See all Kallikrein 7 (KLK7) 蛋白
    Kallikrein 7 (KLK7)
    蛋白类型
    Recombinant
    宿主
    • 13
    • 5
    • 3
    小鼠
    资源
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    人细胞
    标记
    This Kallikrein 7 protein is labelled with His tag.
    原理
    Recombinant Mouse Kallikrein 7/KLK7 Protein (His Tag)
    序列
    Gln22-Arg249
    产品特性
    Recombinant Mouse Kallikrein 7 is produced by our Mammalian expression system and the target gene encoding Gln22-Arg249 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product KLK7 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM HEPES,150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Kallikrein 7 (KLK7)
    别名
    Kallikrein 7/KLK7 (KLK7 产品)
    别名
    Prss6 Protein, SCCE Protein, PRSS6 Protein, hK7 Protein, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) Protein, kallikrein-related peptidase 7 Protein, kallikrein related peptidase 7 Protein, Klk7 Protein, KLK7 Protein
    背景

    Background: Kallikrein7, also named as stratum corneum chymotryptic enzyme (SCCE), is a secreted protein of the Kallikrein-related peptidase (KLK) family. This family contains fifteen homologous secreted serine endopeptidases and plays a significant role in various physiological processes, including skin desquamation, semen liquefaction, neural plasticity, and body fluid homeostasis. In skin KLK5, KLK 7 and KLK14 are able to degrade corneodesmosomes, which leads to desquamation of skin surface cells. KLK activation is believed to be mediated through highly organized proteolytic cascades, regulated through a series of feedback loops, inhibitors, auto-degradation and internal cleavages. Studies have shown that one potential physiological activator for KLK7 is KLK5. Along with KLK14, these three kallikreins form a proteolytic cascade in the stratum corneum. KLK7 is primarily expressed in the skin but is also detected at relatively high levels in esophagus, heart, liver, central nervous system, kidney, pancreas, mammary and salivary glands.

    Synonym: Kallikrein-7, Klk7, Serine protease 6, Stratum corneum chymotryptic enzyme, Thymopsin, kallikrein-related peptidase 7, PRSS6, SCCEkallikrein-7,SCCE

    分子量
    26.1 kDa
    UniProt
    Q91VE3
    途径
    Complement System
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