Kallikrein 7 Protein (KLK7) (His tag)
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- 抗原 See all Kallikrein 7 (KLK7) 蛋白
- Kallikrein 7 (KLK7)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This Kallikrein 7 protein is labelled with His tag.
- 原理
- Recombinant Human Kallikrein 7/KLK7 Protein (His Tag)
- 序列
- Glu23-His252
- 产品特性
- Recombinant Human Kallikrein 7 is produced by our Mammalian expression system and the target gene encoding Glu23-His252 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product KLK7 蛋白
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 150 mM NaCl, pH 7.5.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- Kallikrein 7 (KLK7)
- 别名
- Kallikrein 7/KLK7 (KLK7 产品)
- 别名
- Prss6 Protein, SCCE Protein, PRSS6 Protein, hK7 Protein, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) Protein, kallikrein-related peptidase 7 Protein, kallikrein related peptidase 7 Protein, Klk7 Protein, KLK7 Protein
- 背景
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Background: Human Kallikrein 7 is a member of the tissue kallikrein family of extracellular serine proteases that is made up of 15 members. It is predominantly expressed in the skin. A major physiological function of Kallikrein 7 is to regulate the desquamation process (the shedding of corneocytes from the outer layer of the epidermis) through proteolysis of the intercellular adhesive structures between corneocytes. Dysregulation of Kallikrein 7 has been linked to several inflammatory skin diseases including atopic dermatitis, psoriasis, and Netherton syndrome. Studies have shown that Kallikrein 5 is a potential physiological activator for Kallikrein 7. The proform of Kallikrein 7 can be activated by thermolysin.
Synonym: Kallikrein-7, hK7, Serine Protease 6, Stratum Corneum Chymotryptic Enzyme, hSCCE, KLK7, PRSS6, SCCE
- 分子量
- 26.2 kDa
- UniProt
- P49862
- 途径
- Complement System
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