IL23 Protein (His tag)
-
- 抗原 See all IL23 蛋白
- IL23 (Interleukin 23 (IL23))
- 蛋白类型
- Recombinant
-
宿主
- 小鼠
-
资源
- 人细胞
- 标记
- This IL23 protein is labelled with His tag.
- 原理
- Recombinant Mouse IL-23/Interleukin-23(IL23A&IL12B) Protein (His Tag)
- 序列
- Val22-Ala196&Met23-Ser335
- 产品特性
- Recombinant Mouse Interleukin-23 is produced by our Mammalian expression system and the target geneencoding Val22-Ala196&Met23-Ser335 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product IL23 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- IL23 (Interleukin 23 (IL23))
- 别名
- IL-23/Interleukin-23 (IL23 产品)
- 别名
- IL-23 Protein, p19 Protein, SGRF Protein, il23p19 Protein, interleukin 23, alpha subunit p19 Protein, interleukin 23 subunit alpha Protein, Il23a Protein, IL23A Protein
- 背景
-
Background: Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35 subunit of IL-12, as well as to other single chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. Although p19 is expressed by activated macrophages, dendritic cells, T cells, and endothelial cells, only activated macrophages and dendritic cells express p40 concurrently to produce IL-23. IL-23 has biological activities that are similar to, but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naive and memory human T cells, the effects of IL-23 is restricted to memory T cells.
Synonym: SGRF,IL-23p19,CLMF p40,IL-12 subunit p40,NKSF2
- 分子量
- 9.7&36.8 kDa
-