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IL-2 蛋白

IL2 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7320817
发货至: 中国
  • 抗原 See all IL-2 (IL2) 蛋白
    IL-2 (IL2) (Interleukin 2 (IL2))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 25
    • 12
    • 7
    • 4
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    小鼠
    资源
    • 34
    • 23
    • 17
    • 2
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    • 1
    • 1
    大肠杆菌(E. Coli)
    原理
    Recombinant Mouse Interleukin-2/IL-2 Protein (Active)
    序列
    Ala21-Gln169
    产品特性
    Recombinant Mouse Interleukin-2 is produced by our E.coli expression system and the target gene encoding Ala21-Gln169 is expressed.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. The specific activity of Recombinant Human IL-2 is ≥1x107 IU/mg.
    Top Product
    Discover our top product IL2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM Sodium Citrate, 0.2 % Tween 80, pH 3.0.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    IL-2 (IL2) (Interleukin 2 (IL2))
    别名
    Interleukin-2/IL-2 (IL2 产品)
    别名
    IL2 Protein, IL-2 Protein, il2 Protein, TCGF Protein, lymphokine Protein, Il-2 Protein, POIL2 Protein, interleukin 2 Protein, interleukin-15 Protein, IL2 Protein, il2 Protein, LOC100303688 Protein, Il2 Protein
    背景

    Background: Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2 receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared by cytokine receptors of all members of cytokine family. Mature mouse IL-2 shares 56 % and 73 % aa sequence identity with human and rat IL-2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.Thus, IL-2 may be a key cytokine in the natural suppression of autoimmunity.

    Synonym: IL2, Aldesleukin, Interleukin 2, Interleukin-2, IL-2, IL2, T-cell growth facter, T cell growth factor, TCGF

    分子量
    17.4 kDa
    UniProt
    P04351
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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