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IL17RA Protein (Fc Tag)

IL17RA 宿主: 人 宿主: 人细胞 Recombinant > 90 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7319345
发货至: 中国
  • 抗原 See all IL17RA 蛋白
    IL17RA (Interleukin 17 Receptor A (IL17RA))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 20
    • 9
    • 3
    资源
    • 16
    • 6
    • 5
    • 2
    • 2
    • 1
    人细胞
    标记
    This IL17RA protein is labelled with Fc Tag.
    原理
    Recombinant Human IL17RA Protein (Fc Tag)(Active)
    序列
    Leu33-Trp320
    产品特性
    Recombinant Human Interleukin-17 receptor A is produced by our Mammalian expression system and the target gene encoding Leu33-Trp320 is expressed with a Fc tag at the C-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to inhibit IL-17-induced IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 20-100 ng/ml.
    Top Product
    Discover our top product IL17RA 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    IL17RA (Interleukin 17 Receptor A (IL17RA))
    别名
    IL17RA (IL17RA 产品)
    别名
    IL17R Protein, CANDF5 Protein, CD217 Protein, CDw217 Protein, IL-17RA Protein, hIL-17R Protein, Il17r Protein, AW538159 Protein, Cdw217 Protein, VDw217 Protein, interleukin 17 receptor A Protein, IL17RA Protein, Il17ra Protein
    背景

    Background: Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.

    Synonym: CD127,CDW127,IL-17R,IL-17R-alpha,IL7RA,ILRA, IL-17RA, IL-17 R alpha, Interleukin-17 receptor A

    分子量
    60.6 kDa
    NCBI登录号
    NP_055154
    途径
    SARS-CoV-2 Protein Interactome
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