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IL15RA Protein (Fc Tag)

IL15RA 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7318601
发货至: 中国
  • 抗原 See all IL15RA 蛋白
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 13
    • 4
    • 1
    资源
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    人细胞
    标记
    This IL15RA protein is labelled with Fc Tag.
    原理
    Recombinant Human IL15RA/IL-15RA Protein (Fc Tag)(Active)
    序列
    Ile31-Thr 205
    产品特性
    Recombinant Human Interleukin-15 receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Ile31-Thr205 is expressed with a Fc tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to block human IL-15-induced proliferation of CTLL-2 mouse cytotoxic T cells. The ED50 for this effect is 0.35-3.5 ng/ml.
    Top Product
    Discover our top product IL15RA 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    别名
    IL15RA/IL-15RA (IL15RA 产品)
    别名
    IL15RA Protein, CD215 Protein, AA690181 Protein, IL-15RA Protein, interleukin 15 receptor subunit alpha Protein, interleukin 15 receptor, alpha chain Protein, IL15RA Protein, Il15ra Protein
    背景

    Background: Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and ""transpresent"" cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor β and γ heterodimers and enables signaling to cells.

    Synonym: CD215, IL15RA, CD215 antigen, IL-15 receptor subunit alpha, IL-15RA, IL-15R-alpha, interleukin 15 receptor, alpha, interleukin-15 receptor subunit alpha, MGC104179

    分子量
    45.5 kDa
    UniProt
    Q13261
    途径
    JAK/STAT Signaling
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