IL15RA Protein (Fc Tag)
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- 抗原 See all IL15RA 蛋白
- IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 人细胞
- 标记
- This IL15RA protein is labelled with Fc Tag.
- 原理
- Recombinant Human IL15RA/IL-15RA Protein (Fc Tag)(Active)
- 序列
- Ile31-Thr 205
- 产品特性
- Recombinant Human Interleukin-15 receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Ile31-Thr205 is expressed with a Fc tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to block human IL-15-induced proliferation of CTLL-2 mouse cytotoxic T cells. The ED50 for this effect is 0.35-3.5 ng/ml.
- Top Product
- Discover our top product IL15RA 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
- 别名
- IL15RA/IL-15RA (IL15RA 产品)
- 别名
- IL15RA Protein, CD215 Protein, AA690181 Protein, IL-15RA Protein, interleukin 15 receptor subunit alpha Protein, interleukin 15 receptor, alpha chain Protein, IL15RA Protein, Il15ra Protein
- 背景
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Background: Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and ""transpresent"" cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor β and γ heterodimers and enables signaling to cells.
Synonym: CD215, IL15RA, CD215 antigen, IL-15 receptor subunit alpha, IL-15RA, IL-15R-alpha, interleukin 15 receptor, alpha, interleukin-15 receptor subunit alpha, MGC104179
- 分子量
- 45.5 kDa
- UniProt
- Q13261
- 途径
- JAK/STAT Signaling
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