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IL-11 蛋白

IL11 宿主: 人 宿主: Yeast (Pichia pastoris) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319568
发货至: 中国
  • 抗原 See all IL-11 (IL11) 蛋白
    IL-11 (IL11) (Interleukin 11 (IL11))
    蛋白类型
    Recombinant
    宿主
    • 11
    • 8
    • 2
    • 2
    资源
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Yeast (Pichia pastoris)
    原理
    Recombinant Human Interleukin-11/IL-11 Protein
    序列
    Gly23-Leu199
    产品特性
    Recombinant Human Interleukin-11 is produced by our Yeast expression system and the target gene encoding Gly23-Leu199 is expressed.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product IL11 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 2 % Glycine, pH 7.2.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    IL-11 (IL11) (Interleukin 11 (IL11))
    别名
    Interleukin-11/IL-11 (IL11 产品)
    别名
    IL11 Protein, AGIF Protein, IL-11 Protein, Il-11 Protein, interleukin 11 Protein, IL11 Protein, Il11 Protein
    背景

    Background: Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. IL-11 is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. It also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2, It activates a signaling cascade that promotes cell proliferation. The signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.

    Synonym: Interleukin-11, IL-11, Adipogenesis Inhibitory Factor, AGIF, Oprelvekin, IL11

    分子量
    19 kDa
    UniProt
    P20809
    途径
    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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