IL1A 蛋白
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- 抗原 See all IL1A 蛋白
- IL1A (Interleukin 1 alpha (IL1A))
- 蛋白类型
- Recombinant
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宿主
- 大鼠
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资源
- 大肠杆菌(E. Coli)
- 原理
- Recombinant Rat IL-1A/ IL-1α Protein
- 序列
- Ser115-Ser270
- 产品特性
- Recombinant Rat Interleukin-1 Alpha is produced by our E.coli expression system and the target gene encoding Ser115-Ser270 is expressed.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- <1.0 EU per μg as determined by LAL test.
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- Discover our top product IL1A 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- IL1A (Interleukin 1 alpha (IL1A))
- 别名
- IL-1A/ IL-1alpha (IL1A 产品)
- 别名
- IL-1A Protein, IL1 Protein, IL1-ALPHA Protein, IL1F1 Protein, IL-6 Protein, Il-1a Protein, IL-1 alpha Protein, IL-1alpha Protein, L1A Protein, interleukin 1 alpha Protein, interleukin 6 Protein, IL1A Protein, IL6 Protein, Il1a Protein
- 背景
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Background: Interleukin 1 (IL-1) is a name that designates two proteins, IL-1αand IL-1β, which are the products of distinct genes, but which show approximately 25 % amino acid (aa) sequence identity and which recognize the same cell surface receptors. IL-1αand IL-1β are both synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17,000 Da. Neither precursor contains a typical hydrophobic signal peptide sequence and most of the precursor form of IL-1α remains in the cytosol of cells, although there is evidence for a membranebound form of the precursor form of IL-1α. Although IL-1 production is generally considered to be a consequence of inflammation, evidence suggests that IL-1 is also temporally upregulated during bone formation and the menstrual cycle and can be induced in response to nervous system stimulation. In response to classic stimuli produced by inflammatory agents, infections or microbial endotoxins, a dramatic increase in the production of IL-1 by macrophages and various other cells is seen.
Synonym: Interleukin-1 alpha, IL-1 alpha, Il1a
- 分子量
- 17.9 kDa
- UniProt
- P16598
- 途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
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