IDE Protein (His tag)
Quick Overview for IDE Protein (His tag) (ABIN7318623)
抗原
See all IDE 蛋白蛋白类型
宿主
资源
纯度
-
-
标记
- This IDE protein is labelled with His tag.
-
原理
- Recombinant Human IDE/Insulysin Protein (His Tag)
-
序列
- Met42-Leu1019
-
产品特性
- Recombinant Human Insulin-Degrading Enzyme is produced by our Mammalian expression system and the target gene encoding Met42-Leu1019 is expressed with a 6His tag at the C-terminus.
-
内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
-
-
想要此Protein的其他选项吗？
!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 106,314.67 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 172,528.32 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
-
Insulin-Degrading Enzyme (IDE) (AA 1-1019) protein (His tag)
custom-made IDE 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Insulin-Degrading Enzyme (IDE) (AA 1-1019) protein (His tag)custom-made IDE 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Insulin-Degrading Enzyme (IDE) (AA 920-1019) protein (GST tag)IDE 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Insulin-Degrading Enzyme (IDE) (AA 1-1019) protein (GST tag)IDE 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Insulin-Degrading Enzyme (IDE) protein (Myc-DYKDDDDK Tag)IDE 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
限制
- 仅限研究用
-
-
-
状态
- Frozen, Liquid
-
缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,0.05 % Brij35,10 %Glycerol, pH 7.5.
-
储存条件
- -20 °C
-
储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
-
- IDE (Insulin-Degrading Enzyme (IDE))
-
别名
- IDE/Insulysin
-
背景
-
Background: Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling. IDE degrades amyloid formed by APP and IAPP. IDE may participate in the degradation and clearance of naturally secreted amyloid β-protein by neurons and microglia. IDE, which migrates at 110 kDa during gel electrophoresis under denaturing conditions, has since been shown to have additional substrates, including the signaling peptides glucagon, TGF α and β-endorphin.
Synonym: Insulin-Degrading Enzyme, Abeta-Degrading Protease, Insulin Protease, Insulinase, Insulysin, IDE
-
分子量
- 114.3 kDa
-
UniProt
- P14735
-
途径
- SARS-CoV-2 Protein Interactome
抗原
-
