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Hemopexin Protein (HPX) (His tag)

HPX 宿主: 人 宿主: HEK-293 Cells Recombinant > 96 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7317735
发货至: 中国
  • 抗原 See all Hemopexin (HPX) 蛋白
    Hemopexin (HPX)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 9
    • 6
    • 5
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This Hemopexin protein is labelled with His tag.
    原理
    Recombinant Human Hemopexin/HPX Protein (His Tag)(Active)
    序列
    Met 1-His 462
    产品特性
    A DNA sequence encoding the human HPX (NP_000604.1) (Met 1-His 462) with a C-terminal polyhistidine tag was expressed.
    纯度
    > 96 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to bind protoporphyrin IX (PPPIX). Recombinant human Hemopexin binds > 10 μM PPPIX, resulting in a 50% decrease in the fluorescence signal of human Hemopexin.
    Top Product
    Discover our top product HPX 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Hemopexin (HPX)
    别名
    Hemopexin/HPX (HPX 产品)
    别名
    HPX Protein, HX Protein, Hpxn Protein, hx Protein, wu:fi17f11 Protein, wu:fi19a10 Protein, hemopexin Protein, HPX Protein, Mmar10_1124 Protein, Hpx Protein, hpx Protein
    背景

    Background: GPR114 belongs to the G-protein coupled receptor 2 family. Members of this family share a common molecular architecture which consists of seven transmembrane domains, three extracellular loops, three intracellular loops, an amino-terminal extracellular domain and an intracellular carboxyl terminus. It is thought that light acts as the activating stimulus of a G-protein-coupled receptor (GPCR). GPCRs are expected to have molecular function (G-protein coupled receptor activity) and to localize in various compartments (endoplasmic reticulum membrane, plasma membrane, integral to membrane). Family B of the GPCRs is a small but structurally and functionally diverse group of proteins that includes receptors for polypeptide hormones, molecules thought to mediate intercellular interactions at the plasma membrane and a group of Drosophila proteins that regulate stress responses and longevity. GPR114 contains 1 GPS domain. GPR114 gene has been proposed to participate in processes (G-protein coupled receptor protein signaling pathway, neuropeptide signaling pathway).

    Synonym: Hemopexin,Hpx,Hpxn

    分子量
    50.7 kDa
    NCBI登录号
    NP_000604
    途径
    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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