GDF11 蛋白
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- 抗原 See all GDF11 蛋白
- GDF11 (Growth Differentiation Factor 11 (GDF11))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 原理
- Recombinant Human GDF11/BMP-11 Protein
- 序列
- Asn299-Ser407
- 产品特性
- Recombinant Human Growth differentiation factor 11 is produced by our Mammalian expression system and the target gene encoding Asn299-Ser407 is expressed.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product GDF11 蛋白
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Growth Differentiation Factor 11 (GDF11) (AA 310-407) protein (GST tag)
GDF11 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- GDF11 (Growth Differentiation Factor 11 (GDF11))
- 别名
- GDF11/BMP-11 (GDF11 产品)
- 别名
- BMP-11 Protein, BMP11 Protein, Bmp11 Protein, GDF11 Protein, growth differentiation factor 11 Protein, GDF11 Protein, Gdf11 Protein, gdf11 Protein
- 背景
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Background: Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development.
Synonym: Growth/differentiation factor 11,GDF-11,Bone morphogenetic protein 11,BMP-11
- 分子量
- 12.6 kDa
- UniProt
- O95390
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