GLO1 Protein (His tag)
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- 抗原 See all GLO1 蛋白
- GLO1 (Glyoxalase I (GLO1))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This GLO1 protein is labelled with His tag.
- 原理
- Recombinant Mouse GLO1/Glyoxalase 1 Protein (His Tag)
- 序列
- Ala 2-Ile 184
- 产品特性
- A DNA sequence encoding the mouse GLO1 (NP_079650.3) (Ala 2-Ile 184) was expressed, with a polyhistide tag at the N-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- Top Product
- Discover our top product GLO1 蛋白
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Glyoxalase I (GLO1) (AA 1-184) protein
GLO1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Glyoxalase I (GLO1) (AA 2-184) protein (His tag)GLO1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Glyoxalase I (GLO1) (AA 1-184) protein (GST tag)GLO1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Glyoxalase I (GLO1) (AA 1-184) (Active) protein (His tag)GLO1 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS Active
Glyoxalase I (GLO1) protein (Myc-DYKDDDDK Tag)GLO1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- GLO1 (Glyoxalase I (GLO1))
- 别名
- GLO1/Glyoxalase 1 (GLO1 产品)
- 背景
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Background: Lactoylglutathione lyase, also known as Methylglyoxalase, Aldoketomutase, Glyoxalase I, Ketone-aldehyde mutase, S-D-lactoylglutathione methylglyoxal lyase and GLO1, is a member of the glyoxalase I family. GLO1 / Glyoxalase I is a ubiquitous cellular defense enzyme involved in the detoxification of methylglyoxal, a cytotoxic byproduct of glycolysis. Accumulative evidence suggests an important role of GLO1 expression in protection against methylglyoxal-dependent protein adduction and cellular damage associated with diabetes, cancer, and chronological aging. GLO1 / Glyoxalase I has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. GLO1 / Glyoxalase I catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. GLO1 / Glyoxalase I exists in three separable isoforms which originate from two alleles in the genome. These correspond to two homodimers and one heterodimer composed of two subunits showing different electrophoretic properties. GLO1 upregulation may play a functional role in glycolytic adaptations of cancer cells.
Synonym: 0610009E22Rik,1110008E19Rik,2510049H23Rik,AW550643,Glo-1,Glo-1r,Glo-1s,Glo1-r,Glo1-s,GLY1,Qglo
- 分子量
- 21.6 kDa
- NCBI登录号
- NP_079650
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