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Glutathione Synthetase Protein (GSS) (His tag)

GSS 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318542
发货至: 中国
  • 抗原 See all Glutathione Synthetase (GSS) 蛋白
    Glutathione Synthetase (GSS)
    蛋白类型
    Recombinant
    宿主
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    资源
    • 8
    • 4
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This Glutathione Synthetase protein is labelled with His tag.
    原理
    Recombinant Human GSS Protein (His Tag)
    序列
    Ala2-Val474
    产品特性
    Recombinant Human Glutathione Synthetase is produced by our E.coli expression system and the target gene encoding Ala2-Val474 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product GSS 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 200 mM NaCl, pH 7.5 .
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    Glutathione Synthetase (GSS)
    别名
    GSS (GSS 产品)
    背景

    Background: Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in Glutathione Synthetase can also cause the glutathione synthetase deficiency of erythrocytes, which is a mild form causing hemolytic anemia.

    Synonym: Glutathione Synthetase, GSH Synthetase, GSH-S, Glutathione Synthase, GSS

    分子量
    53.5 kDa
    UniProt
    P48637
    途径
    Warburg Effect
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