FGF12 蛋白
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- 抗原 See all FGF12 蛋白
- FGF12 (Fibroblast Growth Factor 12 (FGF12))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 原理
- Recombinant Human FGF-12/FGF12 Protein (Active)
- 序列
- Met 1-Thr181
- 产品特性
- Recombinant Human Fibroblast Growth Factor 12 is produced by our E.coli expression system and the target gene encoding Met1-Thr181 is expressed.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human FGF-12 at 2ug/ml(100 μl/well) can bind Human FGFR3-Fc(Cat: PKSH033678). The ED50 of Human FGF-12 is 1.27 ug/ml .
- Top Product
- Discover our top product FGF12 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 mM EDTA, pH 7.5.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- FGF12 (Fibroblast Growth Factor 12 (FGF12))
- 别名
- FGF-12/FGF12 (FGF12 产品)
- 别名
- FHF1 Protein, FHF-1 Protein, MGC84150 Protein, FGF12 Protein, fgf12 Protein, zgc:153104 Protein, fhf1 Protein, fgf12b Protein, DKFZp459P139 Protein, FGF12B Protein, AV114868 Protein, FGF-12 Protein, Fhf1 Protein, Fhf1b Protein, fibroblast growth factor 12 Protein, fibroblast growth factor 12 S homeolog Protein, fibroblast growth factor 12a Protein, FGF12 Protein, fgf12.S Protein, fgf12a Protein, fgf12 Protein, Fgf12 Protein
- 背景
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Background: Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast growth factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfectedinto mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
Synonym: Fibroblast Growth Factor 12, FGF-12, Fibroblast Growth Factor Homologous Factor 1, FHF-1, Myocyte-Activating Factor, FGF12, FGF12B, FHF1
- 分子量
- 20.5 kDa
- 途径
- Negative Regulation of Transporter Activity
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