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EPH Receptor A7 Protein (EPHA7) (His tag)

EPHA7 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7319624
发货至: 中国
  • 抗原 See all EPH Receptor A7 (EPHA7) 蛋白
    EPH Receptor A7 (EPHA7)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 10
    • 4
    • 3
    资源
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人细胞
    标记
    This EPH Receptor A7 protein is labelled with His tag.
    原理
    Recombinant Human EphA7/EHK3 Protein (His Tag)(Active)
    序列
    Gln28-Ile556
    产品特性
    Recombinant Human EphA7 is produced by our Mammalian expression system and the target gene encoding Gln28-Ile556 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Immobilized Human EphA7-His at 2μg/ml(100 μl/well) can bind Human EFNA4-Fc-6His(Cat: PKSH032392). The ED50 of Human EphA7-His is 1.5190 ug/ml .
    Top Product
    Discover our top product EPHA7 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    EPH Receptor A7 (EPHA7)
    别名
    EphA7/EHK3 (EPHA7 产品)
    别名
    fc51g03 Protein, wu:fc51g03 Protein, si:dkey-23k6.1 Protein, EHK3 Protein, HEK11 Protein, Cek11 Protein, Ebk Protein, Ehk3 Protein, Hek11 Protein, Mdk1 Protein, CEPHA7 Protein, EPH receptor A7 Protein, eph receptor A7 Protein, ephrin type-B receptor 1-B Protein, Eph receptor A7 Protein, EPHA7 Protein, epha7 Protein, LOC100166161 Protein, Epha7 Protein
    背景

    Background: Ephrin Type-A Receptor 7 (EPHA7) is a single-pass type I membrane protein which belongs to the Eph family of transmembrane receptor tyrosine kinases. It contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile alpha motif) domain. EPHA7 is a receptor for members of the ephrin-A family. Eph receptors are largely expressed throughout the ectoderm, mesoderm, and endoderm of vertebrate embryos. EPHA7 functions as a repulsive guidance molecule during the targeting of retinal axons to the superior colliculus and of neocortical axons to the thalamus. EPHA7 is expressed at a substantial level in most human lung cancers. The high expression of EPHA7 protein may participate in the malignancy transformation, invasion progression and metastasis of primary hepatocellular carcinoma. EPHA7 may involve in smoking related lung carcinogenesis.

    Synonym: Ephrin Type-A Receptor 7, EPH Homology Kinase 3, EHK-3, EPH-Like Kinase 11, EK11, hEK11, EPHA7, EHK3, HEK11

    分子量
    60.19 kDa
    UniProt
    Q15375
    途径
    RTK signaling
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