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DKK3 Protein (His tag)

宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318405
发货至: 中国
  • 抗原 See all DKK3 products
    DKK3
    蛋白类型
    Recombinant
    宿主
    • 10
    • 4
    • 1
    • 1
    资源
    • 8
    • 4
    • 1
    • 1
    • 1
    • 1
    人细胞
    标记
    This DKK3 protein is labelled with His tag.
    原理
    Recombinant Human DKK3 Protein (His Tag)
    序列
    Ala22-Ile350
    产品特性
    Recombinant Human Dickkopf-Related Protein 3 is produced by our Mammalian expression system and the target gene encoding Ala22-Ile350 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    DKK3
    Abstract
    DKK3 产品
    别名
    REIC Protein, RIG Protein, reic Protein, dkk-3 Protein, AW061014 Protein, C87148 Protein, Reic Protein, p29 Protein, dickkopf WNT signaling pathway inhibitor 3 Protein, dickkopf WNT signaling pathway inhibitor 3 S homeolog Protein, DKK3 Protein, dkk3 Protein, dkk3.S Protein, Dkk3 Protein
    背景

    Background: Dickkopf-related protein 3 (DKK3) belongs to the DKK protein family including Dkk-1, 2, 3 and -4. DKK3 is a 350 amino acid secreted glycoprotein which is comprised of an N-terminal signal peptide and 2 conserved cysteine-rich domains that are separated by a 12 amino acid linker region. Dkk-3 also have one prokineticin domain. DKK3 is involved in embryonic development through its inhibition of the WNT signaling pathway. The Dkk family also includes Soggy, which is homologous to Dkk-3 but not to the other family members. Soggy has not been shown to inhibit Wnt signaling, and its role in the pathway is unclear.

    Synonym: Dickkopf-Related Protein 3, Dickkopf-3, Dkk-3, hDkk-3, DKK3, REIC

    分子量
    37.2 kDa
    UniProt
    Q9UBP4
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