DPP10 Protein (His tag)
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- 抗原 See all DPP10 蛋白
- DPP10 (Dipeptidylpeptidase 10 (DPP10))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This DPP10 protein is labelled with His tag.
- 原理
- Recombinant Human DPP10/DPRP3 Protein (His Tag)
- 序列
- Leu 56-Glu 796
- 产品特性
- A DNA sequence encoding the human DPP10 isoform 1 (Q8N608-1) extracellular domain (Leu 56-Glu 796) was expressed, with a polyhistidine tag at the N-terminus.
- 纯度
- > 97 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product DPP10 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- DPP10 (Dipeptidylpeptidase 10 (DPP10))
- 别名
- DPP10/DPRP3 (DPP10 产品)
- 别名
- DPL2 Protein, DPPY Protein, DPRP3 Protein, DPP10 Protein, MGC84485 Protein, 6430601K09Rik Protein, DPP X Protein, Dprp3 Protein, dipeptidyl peptidase like 10 Protein, dipeptidyl-peptidase 10 (inactive) L homeolog Protein, dipeptidylpeptidase 10 Protein, DPP10 Protein, dpp10.L Protein, Dpp10 Protein
- 背景
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Background: Inactive dipeptidyl peptidase 10, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3, DPL2 and DPP10, is a single-pass type I I membrane protein which belongs to the peptidase S9B family. DPPIV subfamily. It may modulate cell surface expression and activity of the potassium channels KCND1 and KCND2. DPP10 / DPRP3 has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Genetic variations in DPP10 are associated with susceptibility to asthma (ASTHMA). The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi.
Synonym: DPL2;DPPY;DPRP-3;DPRP3
- 分子量
- 87.4 kDa
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