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DPP10 Protein (His tag)

DPP10 宿主: 人 宿主: HEK-293 Cells Recombinant > 97 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317488
发货至: 中国
  • 抗原 See all DPP10 蛋白
    DPP10 (Dipeptidylpeptidase 10 (DPP10))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 2
    资源
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This DPP10 protein is labelled with His tag.
    原理
    Recombinant Human DPP10/DPRP3 Protein (His Tag)
    序列
    Leu 56-Glu 796
    产品特性
    A DNA sequence encoding the human DPP10 isoform 1 (Q8N608-1) extracellular domain (Leu 56-Glu 796) was expressed, with a polyhistidine tag at the N-terminus.
    纯度
    > 97 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product DPP10 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    DPP10 (Dipeptidylpeptidase 10 (DPP10))
    别名
    DPP10/DPRP3 (DPP10 产品)
    别名
    DPL2 Protein, DPPY Protein, DPRP3 Protein, DPP10 Protein, MGC84485 Protein, 6430601K09Rik Protein, DPP X Protein, Dprp3 Protein, dipeptidyl peptidase like 10 Protein, dipeptidyl-peptidase 10 (inactive) L homeolog Protein, dipeptidylpeptidase 10 Protein, DPP10 Protein, dpp10.L Protein, Dpp10 Protein
    背景

    Background: Inactive dipeptidyl peptidase 10, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3, DPL2 and DPP10, is a single-pass type I I membrane protein which belongs to the peptidase S9B family. DPPIV subfamily. It may modulate cell surface expression and activity of the potassium channels KCND1 and KCND2. DPP10 / DPRP3 has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Genetic variations in DPP10 are associated with susceptibility to asthma (ASTHMA). The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi.

    Synonym: DPL2;DPPY;DPRP-3;DPRP3

    分子量
    87.4 kDa
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