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DPP10 Protein (His tag)

This Recombinant DPP10 protein is expressed in HEK-293 Cells.
产品编号 ABIN7317488
发货至: 中国

Quick Overview for DPP10 Protein (His tag) (ABIN7317488)

抗原

See all DPP10 蛋白
DPP10 (Dipeptidylpeptidase 10 (DPP10))

蛋白类型

Recombinant

宿主

  • 5
  • 3

资源

  • 3
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

纯度

> 97 % as determined by reducing SDS-PAGE.
  • 标记

    This DPP10 protein is labelled with His tag.

    原理

    Recombinant Human DPP10/DPRP3 Protein (His Tag)

    序列

    Leu 56-Glu 796

    产品特性

    A DNA sequence encoding the human DPP10 isoform 1 (Q8N608-1) extracellular domain (Leu 56-Glu 796) was expressed, with a polyhistidine tag at the N-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 136,947.45 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 172,528.32 ¥

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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    DPP10 (Dipeptidylpeptidase 10 (DPP10))

    别名

    DPP10/DPRP3

    背景

    Background: Inactive dipeptidyl peptidase 10, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3, DPL2 and DPP10, is a single-pass type I I membrane protein which belongs to the peptidase S9B family. DPPIV subfamily. It may modulate cell surface expression and activity of the potassium channels KCND1 and KCND2. DPP10 / DPRP3 has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Genetic variations in DPP10 are associated with susceptibility to asthma (ASTHMA). The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi.

    Synonym: DPL2;DPPY;DPRP-3;DPRP3

    分子量

    87.4 kDa
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