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DPP7 Protein (His tag)

DPP7 宿主: 人 宿主: HEK-293 Cells Recombinant > 98 % as determined by reducing SDS-PAGE.
产品编号 ABIN7195431
发货至: 中国
  • 抗原 See all DPP7 蛋白
    DPP7 (Dipeptidyl-Peptidase 7 (DPP7))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    • 1
    资源
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This DPP7 protein is labelled with His tag.
    原理
    Recombinant Human DPP7/DPPII/DPP2 Protein (His Tag)
    序列
    Met 1-Leu 492
    产品特性
    A DNA sequence encoding the human DPPII (NP_037511.2) (Met 1-Leu 492) with a C-terminal polyhistidine tag was expressed.
    纯度
    > 98 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product DPP7 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    DPP7 (Dipeptidyl-Peptidase 7 (DPP7))
    别名
    DPP7/DPPII/DPP2 (DPP7 产品)
    别名
    DPP2 Protein, DPPII Protein, QPP Protein, Dpp2 Protein, wu:fb19g02 Protein, zgc:112274 Protein, zgc:113564 Protein, DPP7 Protein, MGC151556 Protein, dipeptidyl peptidase 7 Protein, dipeptidylpeptidase 7 Protein, dipeptidyl-peptidase 7 Protein, DPP7 Protein, Dpp7 Protein, Shewana3_0712 Protein, Kkor_1052 Protein, Riean_0388 Protein, dpp7 Protein, Isop_1372 Protein
    背景

    Background: DPP7 (dipeptidylpeptidase 7), also known as DPPII and DPP2, is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. Dipeptidyl peptidases (DPPs) have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. It localizes to lysosomes. DPP7 localizes to lysosomes and exists as a homodimer via its leucine zipper motif and is involved in the degradation of oligopeptides. In response to calcium release, it can be secreted in its active form. It is essential for lymphocyte survival, as the inhibition of DPP7 results in quiescent cell apoptosis.

    Synonym: DPP2,DPPII,QPP

    分子量
    53.6 kDa
    NCBI登录号
    NP_037511
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