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Dermatopontin Protein (DPT) (Fc Tag)

DPT 宿主: 小鼠 宿主: 人细胞 Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7320839
发货至: 中国
  • 抗原 See all Dermatopontin (DPT) 蛋白
    Dermatopontin (DPT)
    蛋白类型
    Recombinant
    宿主
    • 7
    • 2
    • 1
    • 1
    • 1
    小鼠
    资源
    • 4
    • 3
    • 2
    • 2
    • 1
    人细胞
    标记
    This Dermatopontin protein is labelled with Fc Tag.
    原理
    Recombinant Mouse Dermatopontin/DPT Protein (Fc Tag)
    序列
    Gln19-Val201
    产品特性
    Recombinant Mouse Dermatopontin is produced by our Mammalian expression system and the target gene encoding Gln19-Val201 is expressed with a Fc tag at the C-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Dermatopontin (DPT)
    别名
    Dermatopontin/DPT (DPT 产品)
    别名
    MGC108277 Protein, TRAMP Protein, 1810032B19Rik Protein, 5033416F05Rik Protein, EQ-1 Protein, Eq1 Protein, dermatopontin Protein, DPT Protein, dpt Protein, Dpt Protein
    背景

    Background: Platelet Glycoprotein 4(CD36) is belongs to the class B scavenger receptor family. The molecule CD36 is synthesized as a 472 amino acid (aa) protein that contains a 6 aa N-terminal cytoplasmic domain, a 22 aa N-terminal transmembrane segment, a 420 aa extracellular ""loop"", a 22 aa C-terminal transmembrane segment, and a 9 aa C-terminal cytoplasmic tail. Both cytoplasmic tails are palmitoylated, with the C-terminal tail involved in oxidized LDL binding. With respect to the extracellular loop, the N-terminal region is believed to bind both thrombospondin-1 and Plasmodium-infected erythrocytes. Other ligands for CD36 include long-chain fatty acids, collagen, phospholipids and apoptotic cells. Cells known to express CD36 include capillary endothelium, adipocytes, skeletal muscle cells, intestinal epithelium, smooth muscle cells and hematopoietic cells such as RBC's, platelets and monocytes. On the surface of cells, CD36 is suggested to exist as a dimer in response to ligation (7). CD36 is reported to regulate fatty uptake, act as an angiogenic with TSP-1, and participate in the clearance of apoptotic phagocytes.

    Synonym: Early quiescence protein 1, EQ-1, Tyrosine-rich acidic matrix protein, TRAMP

    分子量
    49.1 kDa
    UniProt
    Q9QZZ6
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