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CDCP1 Protein (AA 30-341) (His tag)

CDCP1 宿主: 人 宿主: 人细胞 Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319253
发货至: 中国
  • 抗原 See all CDCP1 蛋白
    CDCP1 (CUB Domain Containing Protein 1 (CDCP1))
    蛋白类型
    Recombinant
    产品特性
    AA 30-341
    宿主
    • 14
    • 7
    • 2
    • 1
    资源
    • 15
    • 5
    • 2
    • 2
    人细胞
    标记
    This CDCP1 protein is labelled with His tag.
    原理
    Recombinant Human CDCP1/CD318 Protein (aa 30-341, His Tag)
    序列
    Phe30-Ser341
    产品特性
    Recombinant Human CUB domain-containing protein 1 is produced by our Mammalian expression system and the target gene encoding Phe30-Ser341 is expressed with a 6His tag at the C-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CDCP1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CDCP1 (CUB Domain Containing Protein 1 (CDCP1))
    别名
    CDCP1/CD318 (CDCP1 产品)
    别名
    CD318 Protein, SIMA135 Protein, TRASK Protein, 9030022E12Rik Protein, AA409659 Protein, E030027H19Rik Protein, RGD1305578 Protein, zgc:113071 Protein, CUB domain containing protein 1 Protein, CUB domain containing protein 1a Protein, CDCP1 Protein, Cdcp1 Protein, cdcp1a Protein
    背景

    Background: CUB domain-containing protein 1(CDCP1) is a transmembrane glycoprotein with a large extracellular domain (ECD) containing two CUB domains, and a smaller intracellular domain (ICD) containing five tyrosines. CDCP1 is widely expressed in human epithelial tissues, but its phosphorylation is only seen in mitotically detached or shedding cells, consistent with its role in the negative regulation of cell adhesion. The tyrosine phosphorylation of CDCP1 in cultured cells occurs when cells are induced to detach by trypsinor EDTA, or seen spontaneously during mitotic detachment. The overexpression of CDCP1 leads to the loss of cell adhesion and a detached phenotype.

    Synonym: CUB domain-containing protein 1,Membrane glycoprotein gp140,Subtractive immunization M plus HEp3-associated 135 kDa protein,SIMA135,Transmembrane and associated with src kinases,CD318,TRASK

    分子量
    36.1 kDa
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