Contactin 4 Protein (CNTN4) (His tag)
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- 抗原 See all Contactin 4 (CNTN4) 蛋白
- Contactin 4 (CNTN4)
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This Contactin 4 protein is labelled with His tag.
- 原理
- Recombinant Human Contactin 4/CNTN4 Protein (His Tag)
- 序列
- Met 1-Ser 1000
- 产品特性
- A DNA sequence encoding the mature form of human CNTN4 isoform 1 (Q8IWV2-1) (Met 1-Ser 1000) was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CNTN4 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.5, 10 % gly
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Contactin 4 (CNTN4)
- 别名
- Contactin 4/CNTN4 (CNTN4 产品)
- 别名
- Axcam Protein, Big-2 Protein, AXCAM Protein, BIG-2 Protein, 9630050B05 Protein, FAR-1 Protein, MGC84491 Protein, zgc:153573 Protein, axcam Protein, big-2 Protein, cntn4a Protein, contactin 4 Protein, contactin 4 S homeolog Protein, Cntn4 Protein, CNTN4 Protein, cntn4.S Protein, cntn4 Protein
- 背景
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Background: Contactin-4, abbreviated as CNTN4, is a brain-derived protein belonging to the immunoglobulin superfamily. It has been found high expression in testes, thyroid, small intestine, uterus and brain. This protein is an neuronal membrane protein that functions as an glycosylphosphatidylinositol- anchored cell adhesion molecule. Contactin-4 is considered as a candidate protein responsible for the differentiation potential of human neuroblastoma cells and it has been implicated in some cases of autism and spinocerebellar ataxia type 16. Studies of the cantactin family have revealed a complex pattern of hemophilic and heterophilic interactions that are required for axon growth and pathfinding. Such studies demonstrate that these essential functions are mediated by the combination and juxtaposition of multiple Ig and FNIII domains. Second, these neuronal adhesion molecules demonstrate highly regulated temporal and spatial expression patterns in the CNS. For this reason, the disruption of the regulatory region of the predominant brain-expressed isoform reasonable would be expected to have significant functional consequences.
Synonym: AXCAM;BIG-2
- 分子量
- 110 kDa
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