CLK3 Protein (CLK3) (GST tag)
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- 抗原 See all CLK3 蛋白
- CLK3
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This CLK3 protein is labelled with GST tag.
- 原理
- Recombinant Human CLK3 Protein (GST Tag)
- 序列
- Met 1-Arg 490
- 产品特性
- A DNA sequence encoding the human CLK3 isoform b (NP_003983.2) (Met 1-Arg 490) was fused with the GST tag at the N-terminus.
- 纯度
- > 80 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CLK3 蛋白
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CLK3 (CLK3) (AA 1-490) protein (GST tag)
CLK3 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
CLK3 (CLK3) (AA 36-136) protein (GST tag)CLK3 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 0.5 mM GSH, 0.5 mM PMSF, 25 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CLK3
- 别名
- CLK3 (CLK3 产品)
- 别名
- PHCLK3 Protein, PHCLK3/152 Protein, AI256811 Protein, CDC like kinase 3 Protein, CDC-like kinase 3 Protein, CLK3 Protein, Clk3 Protein
- 背景
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Background: Dual specificity protein kinase CLK3, also known as CDC-like kinase 3, and CLK3, is a member of CMGC Ser/Thr protein kinase family and Lammer subfamily. Mammalian CLK is the prototype for a family of dual specificity kinases (termed Lammer kinases) that have been conserved in evolution. CLK family members have shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. The three members of the CLK family of kinases (CLK1, CLK2, and CLK3) have been shown to undergo conserved alternative splicing to generate catalytically active and inactive isoforms. The human CLK2 and CLK3 are found within the nucleus and display dual-specificity kinase activity. The truncated isoforms, hCLK2(T) and hCLK3(T), colocalize with SR proteins in nuclear speckles. CLK3 may play a role in the development and progression of azoospermia.
Synonym: PHCLK3,PHCLK3/152
- 分子量
- 85 kDa
- NCBI登录号
- NP_003983
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