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CD93 Protein (CD93) (AA 1-580) (His tag)

CD93 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317351
发货至: 中国
  • 抗原 See all CD93 蛋白
    CD93
    蛋白类型
    Recombinant
    产品特性
    AA 1-580
    宿主
    • 11
    • 3
    • 2
    • 1
    资源
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This CD93 protein is labelled with His tag.
    原理
    Recombinant Human CD93/C1QR1 Protein (aa 1-580, His Tag)
    序列
    Met 1-Lys 580
    产品特性
    A DNA sequence encoding the human CD93 (Q9NPY3) extracellular domain (Met 1-Lys 580) was fused with a polyhistidine tag at the C-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD93 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CD93
    别名
    CD93/C1QR1 (CD93 产品)
    别名
    6030404G09Rik Protein, AA145088 Protein, AA4.1 Protein, AW555904 Protein, C1qr1 Protein, C1qrp Protein, Ly68 Protein, C1QR1 Protein, C1qR(P) Protein, C1qRP Protein, CDw93 Protein, ECSM3 Protein, MXRA4 Protein, dJ737E23.1 Protein, C1qRp Protein, CD93 antigen Protein, CD93 molecule Protein, Cd93 Protein, CD93 Protein
    背景

    Background: CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes, neutrophils, endothelial cells, and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR, a receptor expressed during early B-cell development, is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive, memory, and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches.

    Synonym: Complement Component C1q Receptor, C1q/MBL/SPA Receptor, C1qR, C1qR(p), C1qRp, CDw93, Complement Component 1 q Subcomponent Receptor 1, Matrix-Remodeling-Associated Protein 4CD93, C1QR1, MXRA4

    分子量
    59.6 kDa
    UniProt
    Q9NPY3
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