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CD8B Protein (Fc Tag)

CD8B 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319847
发货至: 中国
  • 抗原 See all CD8B 蛋白
    CD8B (CD8b Molecule (CD8B))
    蛋白类型
    Recombinant
    宿主
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    资源
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    人细胞
    标记
    This CD8B protein is labelled with Fc Tag.
    原理
    Recombinant Human CD8 Beta Chain/CD8B (C-Fc)
    序列
    Leu22-Pro170
    产品特性
    Recombinant Human T-Cell Surface Glycoprotein CD8 beta Chain is produced by our Mammalian expression system and the target gene encoding Leu22-Pro170 is expressed with a Fc tag at the C-terminus.
    纯度
    >95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD8B 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CD8B (CD8b Molecule (CD8B))
    别名
    CD8 Beta Chain/CD8B (CD8B 产品)
    别名
    Cd8b Protein, Ly-3 Protein, Ly-C Protein, Lyt-3 Protein, CD8B1 Protein, LEU2 Protein, LY3 Protein, LYT3 Protein, P37 Protein, Cd8b1 Protein, CD8b molecule Protein, CD8 antigen, beta chain 1 Protein, Cd8b Protein, CD8B Protein, Cd8b1 Protein
    背景

    Background: T-Cell Surface Glycoprotein CD8β Chain (CD8 Antigen) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 Antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

    Synonym: T-Cell Surface Glycoprotein CD8 Beta Chain, CD8b, CD8B, CD8B1

    分子量
    43.7 kDa
    UniProt
    P10966
    途径
    TCR Signaling
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