CD8 alpha Protein (Fc Tag)
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- 抗原 See all CD8 alpha (CD8A) 蛋白
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- 蛋白类型
- Recombinant
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This CD8 alpha protein is labelled with Fc Tag.
- 原理
- Recombinant Rat CD8A/MAL Protein (Fc Tag)
- 序列
- Met1-Tyr189
- 产品特性
- A DNA sequence encoding the rat CD8A (P07725) (Met1-Tyr189) was expressed with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 90 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
- Top Product
- Discover our top product CD8A 蛋白
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CD8a Molecule (CD8A) (AA 28-196) protein (His tag)
CD8A 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD8a Molecule (CD8A) (AA 22-182) protein (His-Avi Tag,Biotin)CD8A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD8a Molecule (CD8A) (AA 22-182) (Active) protein (His tag)CD8A 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD8a Molecule (CD8A) (AA 22-182) (Active) protein (His tag,AVI tag,Biotin)CD8A 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD8a Molecule (CD8A) (AA 22-182) protein (His-IF2DI Tag)CD8A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
CD8a Molecule (CD8A) (AA 22-131) protein (GST tag)CD8A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD8a Molecule (CD8A) (AA 1-235) protein (GST tag)CD8A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD8a Molecule (CD8A) (Active) protein (His tag)CD8A 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- 别名
- CD8A/MAL (CD8A 产品)
- 别名
- cd8 Protein, LOC100136450 Protein, BB154331 Protein, Ly-2 Protein, Ly-35 Protein, Ly-B Protein, Lyt-2 Protein, zgc:136643 Protein, CD8 Protein, Leu2 Protein, MAL Protein, p32 Protein, RHACD8-4 Protein, CD8a molecule Protein, uncharacterized LOC100125537 Protein, CD8 alpha Protein, CD8 antigen, alpha chain Protein, T-cell surface glycoprotein CD8 alpha chain Protein, Cd8a Protein, LOC100125537 Protein, LOC100136450 Protein, CD8A Protein, cd8a Protein, LOC100126556 Protein
- 背景
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Background: T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex (MHC) Class I antigens, and in signal transduction during the course of T-cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. The Ig domains of CD8 alpha are involved in controlling the ability of CD8 to be expressed. Mutation of B- and F-strand cysteine residues in CD8 alpha reduced the ability of the protein to fold properly and, therefore, to be expressed. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.
Synonym: CD8A
- 分子量
- 45 kDa
- UniProt
- P07725
- 途径
- TCR Signaling
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