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CD83 Protein (CD83) (Fc Tag)

CD83 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 76 % as determined by SDS-PAGE
产品编号 ABIN7321123
发货至: 中国
  • 抗原 See all CD83 蛋白
    CD83
    蛋白类型
    Recombinant
    宿主
    • 11
    • 5
    • 1
    • 1
    大鼠
    资源
    • 9
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This CD83 protein is labelled with Fc Tag.
    原理
    Recombinant Rat CD83/HB15 Protein (Fc Tag)
    序列
    Met1-Ala134
    产品特性
    A DNA sequence encoding the rat CD83 (B2GV95) (Met1-Ala134) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
    纯度
    > 76 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method
    Top Product
    Discover our top product CD83 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CD83
    别名
    CD83/HB15 (CD83 产品)
    别名
    BL11 Protein, HB15 Protein, CD83 molecule Protein, CD83 antigen Protein, Cd83 Protein, CD83 Protein
    背景

    Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD83 is considered as a marker of mature dendritic cells as well as an adhesion receptor that binds to resting monocytes and a subset of activated CD8+ T cells. In certain conditions, CD83 tended to dimerize or even multimerize through its aberrant intermolecular disulfide bonds. The injection of CD83-Ig can significantly enhaunce the rate of tumor growth and inhibit the T cell growth.

    Synonym: CD83

    分子量
    39.4 kDa
    UniProt
    B2GV95
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