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CD82 Protein (CD82) (Fc Tag)

CD82 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319825
发货至: 中国
  • 抗原 See all CD82 蛋白
    CD82
    蛋白类型
    Recombinant
    宿主
    • 3
    • 2
    资源
    • 2
    • 1
    • 1
    • 1
    人细胞
    标记
    This CD82 protein is labelled with Fc Tag.
    原理
    Recombinant Human CD82 (N-Fc)
    序列
    Gly103-Gln225
    产品特性
    Recombinant Human CD82 Antigen is produced by our Mammalian expression system and the target gene encoding Gly103-Gln225 is expressed with a Fc tag at the N-terminus.
    纯度
    >95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD82 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CD82
    别名
    CD82 (CD82 产品)
    别名
    AA682076 Protein, AL023070 Protein, C33 Protein, IA4 Protein, Kai1 Protein, Tspan27 Protein, 4F9 Protein, GR15 Protein, KAI1 Protein, R2 Protein, SAR2 Protein, ST6 Protein, TSPAN27 Protein, CD82 antigen Protein, CD82 molecule Protein, Cd82 molecule Protein, Cd82 Protein, CD82 Protein
    背景

    Background: CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.

    Synonym: CD82 antigenC33, CD82 Molecule, CD82, IA4, IA4C33 antigen, Inducible membrane protein R2, KAI1, KAI1GR15, ST6, ST6tspan-27, Suppressor of tumorigenicity 6 protein, Tetraspanin-27, TSPAN27, Tspan-27, TSPAN274F9

    分子量
    40.3 kDa
    UniProt
    P27701
    途径
    p53 Pathway
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