CD82 Protein (CD82) (Fc Tag)
-
- 抗原 See all CD82 蛋白
- CD82
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 人细胞
- 标记
- This CD82 protein is labelled with Fc Tag.
- 原理
- Recombinant Human CD82 (N-Fc)
- 序列
- Gly103-Gln225
- 产品特性
- Recombinant Human CD82 Antigen is produced by our Mammalian expression system and the target gene encoding Gly103-Gln225 is expressed with a Fc tag at the N-terminus.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CD82 蛋白
-
CD82 (CD82) (AA 1-267) protein (GST tag)
CD82 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
CD82 (CD82) (AA 111-227), (Extracellular) protein (His-SUMO Tag)CD82 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- CD82
- 别名
- CD82 (CD82 产品)
- 背景
-
Background: CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.
Synonym: CD82 antigenC33, CD82 Molecule, CD82, IA4, IA4C33 antigen, Inducible membrane protein R2, KAI1, KAI1GR15, ST6, ST6tspan-27, Suppressor of tumorigenicity 6 protein, Tetraspanin-27, TSPAN27, Tspan-27, TSPAN274F9
- 分子量
- 40.3 kDa
- UniProt
- P27701
- 途径
- p53 Pathway
-
