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CD38 Protein (His tag)

宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
产品编号 ABIN7194833
发货至: 中国
  • 抗原 See all CD38 蛋白
    CD38
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 21
    • 6
    • 4
    • 3
    • 1
    小鼠
    资源
    • 13
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This CD38 protein is labelled with His tag.
    原理
    Recombinant Mouse CD38 Protein (His Tag)(Active)
    序列
    Leu 45-Thr 304
    产品特性
    A DNA sequence encoding the extracellular domain of mouse CD38 (NP_031672.2) (Leu 45-Thr 304) was expressed, fused with a C-terminal polyhistidine tag.
    纯度
    > 97 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to convert the substrate nicotinamide guanine dinucleotide (NGD+) to cyclic GDPribose. The specific activity is >50,000pmols/min/ug.
    Top Product
    Discover our top product CD38 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 20 mM MES, 0.15M NaCl, pH 6.5
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CD38
    Abstract
    CD38 产品
    别名
    T10 Protein, Cd38-rs1 Protein, cd38 Protein, ADPRC 1 Protein, cADPr hydrolase 1 Protein, CD38 molecule Protein, CD38 antigen Protein, CD38 molecule L homeolog Protein, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Protein, CD38 Protein, Cd38 Protein, cd38.L Protein
    背景

    Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells.

    Synonym: cADPr hydrolase 1, CD38 antigen (p45), CD38 antigen, CD38 Molecule, CD38, Cyclic ADP-ribose hydrolase 1, Cyclic ADP-ribose Hydrolase, EC 3.2.2.5, NAD(+) nucleosidase, T10,ADPRC 1-rs1,ADPRC1,Cd38,Cd38-rs1,I-19

    分子量
    31.3 kDa
    NCBI登录号
    NP_031672
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