CD276 Protein (CD276) (Fc Tag)
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- 抗原 See all CD276 蛋白
- CD276
- 蛋白类型
- Recombinant
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宿主
- Cynomolgus
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资源
- 人细胞
- 标记
- This CD276 protein is labelled with Fc Tag.
- 原理
- Recombinant Cynomolgus B7-H3/CD276 Protein (Fc Tag)
- 序列
- Leu29-Glu465
- 产品特性
- Recombinant Cynomolgus CD276 Molecule is produced by our Mammalian expression system and the target gene encoding Leu29-Glu465 is expressed with a Fc tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CD276 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CD276
- 别名
- B7-H3/CD276 (CD276 产品)
- 背景
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Background: CD276, also known as B7-H3, is a member of the B7 superfamily with signature IgV and IgG regions in extracellular domains. It is a type I transmembrane protein and shares 20-27 % amino acid identity with other B7 family members. B7-H3 is involved in the activation of T lymphocytes, and regulates murine bone formation. It is also reported that B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is expressed on T-cells, natural killer cells, and antigen presenting cells, as well as some non-immune cells, such as osteoblasts, fibroblasts, fibroblast-like synoviocytes and epithelial cells. High expression of B7-H3 in tumor vasculature also correlates with poor survival in patients, suggesting that it may play a role in tumor cell migration.
Synonym: CD276 antigen, CD276, B7 homolog 3, B7-H3,CD276
- 分子量
- 74 kDa
- NCBI登录号
- XP_015308534
- 途径
- Cancer Immune Checkpoints
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