CD226 Protein (CD226) (Fc Tag)
-
- 抗原 See all CD226 蛋白
- CD226
- 蛋白类型
- Recombinant
- 生物活性
- Active
-
宿主
- 人
-
资源
- 人细胞
- 标记
- This CD226 protein is labelled with Fc Tag.
- 原理
- Recombinant Human CD226/DNAM-1 Protein (Fc Tag)(Active)
- 序列
- Glu19-Asn247
- 产品特性
- Recombinant Human CD226 Antigen is produced by our Mammalian expression system and the target gene encoding Glu19-Asn247 is expressed with a Fc tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human DNAM-1-Fc at 2μg/ml(100 μl/well) can bind Human Nectin-2-6His(Cat: PKSH032913). The ED50 of Human DNAM-1-Fc is 0.79 ug/mL
- Top Product
- Discover our top product CD226 蛋白
-
CD226 (CD226) (AA 19-247) protein (Fc Tag)
CD226 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD226 (CD226) (AA 19-247) protein (His-Avi Tag)CD226 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
CD226 (CD226) (AA 19-252) protein (His tag)CD226 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD226 (CD226) (AA 19-247) protein (His-Avi Tag,Biotin)CD226 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
CD226 (CD226) (AA 19-247) protein (mFc-His Tag)CD226 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
CD226 (CD226) (AA 19-252) (Active) protein (His tag)CD226 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD226 (CD226) protein (His tag)CD226 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
CD226 (CD226) (AA 21-127) protein (GST tag)CD226 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
CD226 (CD226) (Active) protein (Fc Tag)CD226 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
CD226 (CD226) (Active) protein (His tag)CD226 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- CD226
- 别名
- CD226/DNAM-1 (CD226 产品)
- 别名
- CD226 Protein, cd226 Protein, zgc:158817 Protein, BC051526 Protein, DNAM-1 Protein, DNAM1 Protein, Pta1 Protein, TLiSA1 Protein, PTA1 Protein, CD226 molecule Protein, CD226 antigen Protein, CD226 Protein, cd226 Protein, Cd226 Protein
- 背景
-
Background: Human DNAX accessory molecule 1 (DNAM-1/CD226) is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily. Mature human DNAM-1 contains an extracellular domain (ECD) with two Ig-like C2-set domains and a cytoplasmic region that contains motifs for binding PDZ domains and band 4.1 family proteins. DNAM-1 is expressed on multiple lymphoid and myeloid cells and interacts with CD155 and CD112. Ligation of DNAM-1 promotes the activation of NK cells, CD8+ T cells, and mast cells, dendritic cell maturation, megakaryocyte and activated platelet adhesion to vascular endothelial cells, and monocyte extravasation, it inhibits the forrmation of osteoclasts. Plateletendothelium, interactions mediated by DNAM-1, enable the metastasis of tumor cells to the lung.
Synonym: CD226 antigen, DNAX accessory molecule 1, DNAM-1, CD226, DNAM1
- 分子量
- 52.8 kDa
- UniProt
- Q15762
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
-
