DC-SIGN/CD209 Protein (Fc Tag)
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- 抗原 See all DC-SIGN/CD209 (CD209) 蛋白
- DC-SIGN/CD209 (CD209) (CD209)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This DC-SIGN/CD209 protein is labelled with Fc Tag.
- 原理
- Recombinant Human DC-SIGN/CD209 (N-Fc)
- 序列
- Gln59-Ala404
- 产品特性
- Recombinant Human CD209 Antigen is produced by our Mammalian expression system and the target gene encoding Gln59-Ala404 is expressed with a Fc tag at the N-terminus.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CD209 蛋白
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CD209 (CD209) (AA 59-404) protein (His tag)
CD209 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD209 (CD209) (AA 1-404) protein (GST tag)CD209 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
CD209 (CD209) (AA 271-380) protein (GST tag)CD209 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
CD209 (CD209) (AA 70-404) protein (T7 tag,His tag)CD209 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant ≥ 94 % ELISA, WB, SDS, IP
CD209 (CD209) (AA 115-238) protein (T7 tag,His tag)CD209 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant ≥ 96 % ELISA, WB, SDS, IP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- DC-SIGN/CD209 (CD209) (CD209)
- 别名
- DC-SIGN/CD209 (CD209 产品)
- 别名
- CDSIGN Protein, CLEC4L Protein, DC-SIGN Protein, DC-SIGN1 Protein, cd209 Protein, CLEC4M Protein, si:ch211-224h1.3 Protein, CD209 Protein, CIRE Protein, Dcsign Protein, SIGN-R1 Protein, SIGNR5 Protein, Cd209 Protein, CD209 molecule Protein, CD209a antigen Protein, CD209 antigen-like protein D Protein, CD209c molecule Protein, CD209 antigen Protein, CD209 Protein, cd209 Protein, Cd209a Protein, LOC100529184 Protein, Cd209c Protein, LOC100460708 Protein, LOC105484282 Protein
- 背景
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Background: CD209 is also known as CLEC4L, DC-SIGN and CD209 antigen, is a type II transmembrane protein on DCs with a C-type lectin extracellular domain, is capable of binding ICAM-3 on resting T cells in the secondary lymphoid organs, providing the initial contact between these cells during the establishment of cell-mediated immunity. The DC-SIGN/CD209 lectin domain binds mannose oligosaccharides on pathogens including HIV as well as self glycoproteins including ICAMs (2, 4). DC-SIGN/CD209 binds to butyrophilin 2A1 and this interaction can be blocked by HIV pp120. DC-SIGN/CD209 is expressed on dendritic cells (DC) and inflammatory macrophages and contributes to antigen presentation. It is not only a pattern recognition receptor but implicated in immunoregulation of DCs. It has important role in mediating DC adhesion, migration, inflammation, activating primary T cell, triggering immune response and participating in immune escape of pathogens and tumors.
Synonym: CD209 Molecule, CD209, CDSIGNHIV gpl20-binding protein, CLEC4L, DCSIGN, DC-SIGN, DC-SIGN1, CD209 Antigen
- 分子量
- 65.3 kDa
- UniProt
- Q9NNX6
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