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Cathepsin S Protein (CTSS) (His tag)

CTSS 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320704
发货至: 中国
  • 抗原 See all Cathepsin S (CTSS) 蛋白
    Cathepsin S (CTSS)
    蛋白类型
    Recombinant
    宿主
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    小鼠
    资源
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    人细胞
    标记
    This Cathepsin S protein is labelled with His tag.
    原理
    Recombinant Mouse Cathepsin S/CTSS Protein (His Tag)
    序列
    Val18-Ile340
    产品特性
    Recombinant Mouse Cathepsin S is produced by our Mammalian expression system and the target gene encoding Val18-Ile340 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CTSS 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Cathepsin S (CTSS)
    别名
    Cathepsin S/CTSS (CTSS 产品)
    别名
    ctss-a Protein, MGC69026 Protein, ctss-b Protein, MGC80097 Protein, ctss.1 Protein, CTSS Protein, ctss Protein, cats Protein, cathepsin S Protein, cathepsin S L homeolog Protein, cathepsin S S homeolog Protein, Cathepsin S Protein, CTSS Protein, Ctss Protein, ctss.L Protein, ctss.S Protein, ctss Protein, cats Protein
    背景

    Background: Cathepsin S is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, cathepsin S is expressed in some epithelial cells. Compared with the abundant cathepsins B, L and H, cathepsin S shows a restricted tissue distribution, with highest levels in spleen, heart, and lung. In addition, evidences indicated that cathepsin S generates A beta from amyloidogenic fragments of beta APP in the endosomal/lysosomal compartment, and is implicated in the pathogenesis of Alzheimer's disease (AD) and Down Syndrome (DS).

    Synonym: Cathepsin S, CTSS

    分子量
    37.5 kDa
    途径
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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