Cathepsin L Protein (His tag)
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- 抗原 See all Cathepsin L (CTSL1) 蛋白
- Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This Cathepsin L protein is labelled with His tag.
- 原理
- Recombinant Human Cathepsin L/CTSL Protein (His Tag)
- 序列
- Thr18-Val333
- 产品特性
- Recombinant Human Cathepsin L is produced by our Mammalian expression system and the target gene encoding Thr18-Val333 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CTSL1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.5.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))
- 别名
- Cathepsin L/CTSL (CTSL1 产品)
- 背景
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Background: Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins involved in growth regulation. Unlike the precursor forms of other papain family members, the 43 kDa pro-cathepsin L itself is secreted from various cells. Pro-cathepsin L is the major excreted protein of malignantly transformed mouse fibroblasts and is also one of the major acidic cysteine proteases in mammalian cells.
Synonym: Cathepsin L1, Major Excreted Protein, MEP, CTSL1, CTSL
- 分子量
- 36.9 kDa
- UniProt
- P07711
- 途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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