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Cathepsin D Protein (CTSD) (His tag)

CTSD 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318253
发货至: 中国
  • 抗原 See all Cathepsin D (CTSD) 蛋白
    Cathepsin D (CTSD)
    蛋白类型
    Recombinant
    宿主
    • 10
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    资源
    • 12
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    人细胞
    标记
    This Cathepsin D protein is labelled with His tag.
    原理
    Recombinant Human Cathepsin D/CTSD Protein (His Tag)
    序列
    Leu21-Leu412
    产品特性
    Recombinant Human Cathepsin D is produced by our Mammalian expression system and the target gene encoding Leu21-Leu412 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CTSD 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    Cathepsin D (CTSD)
    别名
    Cathepsin D/CTSD (CTSD 产品)
    别名
    catD Protein, fb93e11 Protein, fj17b09 Protein, wu:fb93e11 Protein, wu:fj17b09 Protein, LOC398557 Protein, Cathd Protein, CatD Protein, LOC100136761 Protein, CTSD Protein, DKFZp469J0315 Protein, DDBDRAFT_0205785 Protein, DDBDRAFT_0215012 Protein, DDB_0205785 Protein, DDB_0215012 Protein, CLN10 Protein, CPSD Protein, CD Protein, cathepsin D Protein, cathepsin D S homeolog Protein, lysosomal aspartic protease Protein, cathepsin D-like Protein, ctsd Protein, LOC398557 Protein, ctsd.S Protein, CatD Protein, LOC5567565 Protein, LOC100136761 Protein, CTSD Protein, Cathd Protein, ctsD Protein, catd Protein, Ctsd Protein, LOC443060 Protein
    背景

    Background: The protein acid protease active in intracellular protein breakdown and involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. It is specificity similar to, but narrower than, that of pepsin A and it does not cleave the 4-Gln-|-His-5 bond in B chain of insulin. It consists of a light chain and a heavy chain and expressed in the aorta extrcellular space. The Val-58 allele is significantly overrepresented in demented patients (11.8 % ) compared with non-demented controls (4.9 %). Carriers of the Val-58 allele have a 3.1-fold increased risk for developing AD than non-carriers.It belongs to the peptidase A1 family

    Synonym: Cathepsin D, CTSD,CLN10,CPSD,HEL-S-130P

    分子量
    43.8 kDa
    UniProt
    P07339
    途径
    Peptide Hormone Metabolism
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