Cathepsin B Protein (CTSB) (His tag)
-
- 抗原 See all Cathepsin B (CTSB) 蛋白
- Cathepsin B (CTSB)
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 人细胞
- 标记
- This Cathepsin B protein is labelled with His tag.
- 原理
- Recombinant Human Cathepsin B/CTSB Protein (His Tag)
- 序列
- Arg18-Ile339
- 产品特性
- Recombinant Human Cathepsin B is produced by our Mammalian expression system and the target gene encoding Arg18-Ile339 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CTSB 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- 抗原
- Cathepsin B (CTSB)
- 别名
- Cathepsin B/CTSB (CTSB 产品)
- 别名
- APPS Protein, CPSB Protein, CB Protein, apps Protein, cpsb Protein, LOC692390 Protein, CTSB Protein, cathepsin B Protein, cathepsin B S homeolog Protein, CTSB Protein, Ctsb Protein, ctsb.S Protein, LOC692390 Protein
- 背景
-
Background: Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes
Synonym: Cathepsin B, APP Secretase, APPS, Cathepsin B1, CTSB, CPSB
- 分子量
- 36.9 kDa
- UniProt
- P07858
- 途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
-