CTSA Protein (His tag)
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- 抗原 See all CTSA 蛋白
- CTSA (Cathepsin A (CTSA))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CTSA protein is labelled with His tag.
- 原理
- Recombinant Human Cathepsin A/CTSA Protein (His Tag)
- 序列
- Met 1-Tyr 480
- 产品特性
- A DNA sequence encoding the human cathepsin A isoform b (Met 1-Tyr 480) (NP_001121167.1) was expressed with a N-terminal signal peptide and a C-terminal polyhistidine tag.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CTSA 蛋白
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Cathepsin A (CTSA) (AA 24-474) protein (His tag)
CTSA 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
Cathepsin A (CTSA) (AA 1-480) protein (GST tag)CTSA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cathepsin A (CTSA) protein (His tag)CTSA 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 25 mM Tris, 0.15 mM NaCl, pH 7.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CTSA (Cathepsin A (CTSA))
- 别名
- Cathepsin A/CTSA (CTSA 产品)
- 别名
- Ppgb Protein, beta-galactosidase 2 Protein, PPGB Protein, GLB2 Protein, GSL Protein, NGBE Protein, PPCA Protein, AU019505 Protein, cathepsin A Protein, beta-galactosidase 2 Protein, Ctsa Protein, BGAL2 Protein, CTSA Protein
- 背景
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Background: Lysosomal carboxypeptidase, cathepsin A (protective protein, CathA), is a component of the lysosomal multienzyme complex along with beta-galactosidase (GAL) and sialidase Neu1, where it activates Neu1 and protects GAL and Neu1 against the rapid proteolytic degradation. Cathepsin A is a multicatalytic enzyme with deamidase and esterase in addition to carboxypeptidase activities. It was recently identified in human platelets as deamidase. In vitro, it hydrolyzes a variety of bioactive peptide hormones including tachykinins, suggesting that extralysosomal cathepsin A plays a role in regulation of bioactive peptide functions. It is a member of the alpha/beta hydrolase fold family and has been suggested to share a common ancestral relationship with other alpha/beta hydrolase fold enzymes, such as cholinesterases. Cathepsin A defects are linked to multiple forms of Galactosialidosis with a combined secondary deficiency of beta-galactosidase and neuraminidase. Cathepsin A is a key molecule in the onset of galactosialidosis and also highlight the therapeutic acts in vivo as an endothelin-1-inactivating enzyme and strongly confirm a crucial role of this enzyme in effective elastic fiber formation.
Synonym: Lysosomal protective protein,CTSA,Carboxypeptidase C,Carboxypeptidase L,Cathepsin A,GLB2,GSL,NGBE,PPCA,PPGB
- 分子量
- 53 kDa
- NCBI登录号
- NP_001121167
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