Cardiotrophin 1 Protein (CTF1) (His tag)
-
- 抗原 See all Cardiotrophin 1 (CTF1) 蛋白
- Cardiotrophin 1 (CTF1)
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 标记
- This Cardiotrophin 1 protein is labelled with His tag.
- 原理
- Recombinant Human Cardiotrophin-1/CTF1 Protein (His Tag)
- 序列
- Met 1-Ala201
- 产品特性
- Recombinant Human Cardiotrophin-1 is produced by our E.coli expression system and the target gene encoding Met1-Ala201 is expressed with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CTF1 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- 抗原
- Cardiotrophin 1 (CTF1)
- 别名
- Cardiotrophin-1/CTF1 (CTF1 产品)
- 别名
- CTF1 Protein, ct1 Protein, ct-1 Protein, ctf2 Protein, CT-1 Protein, CT1 Protein, cardiotrophin 1 Protein, cardiotrophin-1 Protein, CTF1 Protein, ctf1 Protein, Ctf1 Protein, LOC100736818 Protein
- 背景
-
Background: Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine. The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130)/leukemia inhibitory factor receptor beta (LIFR) heterodimer. In addition, CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and enhances transcription factor NF-κB DNA -binding activities.
Synonym: Cardiotrophin-1, CT-1, CTF1,
- 分子量
- 22.6 kDa
- UniProt
- Q16619
- 途径
- JAK/STAT Signaling
-