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CES1 Protein (His tag)

CES1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318241
发货至: 中国
  • 抗原 See all CES1 蛋白
    CES1 (Carboxylesterase 1 (CES1))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 1
    • 1
    资源
    • 4
    • 3
    • 1
    • 1
    人细胞
    标记
    This CES1 protein is labelled with His tag.
    原理
    Recombinant Human Carboxylesterase 1/CES1 Protein (His Tag)
    序列
    His19-Glu562
    产品特性
    Recombinant Human Carboxylesterase 1 is produced by our Mammalian expression system and the target gene encoding His19-Glu562 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CES1 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.0.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    CES1 (Carboxylesterase 1 (CES1))
    别名
    Carboxylesterase 1/CES1 (CES1 产品)
    别名
    ACAT Protein, CE-1 Protein, CEH Protein, CES2 Protein, HMSE Protein, HMSE1 Protein, PCE-1 Protein, REH Protein, SES1 Protein, TGH Protein, hCE-1 Protein, CESDD1 Protein, CES1 Protein, CES-K1 Protein, APLE Protein, PMPMEase Protein, CES Protein, carboxylesterase 1 Protein, liver carboxylesterase 1 Protein, liver carboxylesterase Protein, carboxylesterase 1 (monocyte/macrophage serine esterase 1) Protein, CES1 Protein, CpipJ_CPIJ013026 Protein, CpipJ_CPIJ016339 Protein, LOC100009551 Protein, LOC454097 Protein, LOC699486 Protein, LOC100050915 Protein
    背景

    Background: Carboxylesterase 1 (CES1) is a member of a large family of carboxylesterases that are responsible for the hydrolysis of ester and amide bonds. These enzymes have broad substrate specificity ranging from small molecule esters such as phenylester to long chain fatty acid esters and thioesters. They are major determinants of the pharmacokinetic behavior of most therapeutic agents containing an ester or amide bond. CES1 shares the serine hydrolase fold observed in other esterases. CES1 hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. CES1 participates in detoxification of drugs such as cocaine and heroin in serum and liver. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds.

    Synonym: Liver Carboxylesterase 1, Acyl-Coenzyme A:Cholesterol Acyltransferase, ACAT, Brain Carboxylesterase hBr1, Carboxylesterase 1, CE-1, hCE-1, Cocaine Carboxylesterase, Egasyn, HMSE, Methylumbelliferyl-Acetate Deacetylase 1, Monocyte/Macrophage Serine Esterase, Retinyl Ester Hydrolase, REH, Serine Esterase 1, Triacylglycerol Hydrolase, TGH, CES1, CES2, SES1

    分子量
    61.1 kDa
    途径
    Monocarboxylic Acid Catabolic Process
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