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Calmodulin 1 Protein (Calm1)

Calm1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318225
发货至: 中国
  • 抗原 See all Calmodulin 1 (Calm1) 蛋白
    Calmodulin 1 (Calm1)
    蛋白类型
    Recombinant
    宿主
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 10
    • 7
    • 1
    • 1
    大肠杆菌(E. Coli)
    原理
    Recombinant Human Calmodulin/CALM1 Protein
    序列
    Met 1-Lys149
    产品特性
    Recombinant Human Calmodulin is produced by our E.coli expression system and the target gene encoding Met1-Lys149 is expressed.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product Calm1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 50 mM NH4HCO3, pH 8.0 .
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Calmodulin 1 (Calm1)
    别名
    Calmodulin/CALM1 (Calm1 产品)
    别名
    AI256814 Protein, AI327027 Protein, AI461935 Protein, AL024000 Protein, CaM Protein, Calm Protein, CaMI Protein, CALML2 Protein, CAMI Protein, CPVT4 Protein, DD132 Protein, LQT14 Protein, PHKD Protein, caM Protein, calm1 Protein, calm2-a Protein, calm2-b Protein, calm2a Protein, calml2 Protein, cami Protein, dd132 Protein, 3909 Protein, CAM Protein, CG8472 Protein, Cal Protein, Cal49A Protein, CalA Protein, Cam1 Protein, D-CaM Protein, DmCaM Protein, DmCalm Protein, Dmel\CG8472 Protein, anon-EST:Posey59 Protein, cam Protein, dCaM Protein, l(2)03909 Protein, l(2)3909 Protein, lincRNA.S2634 Protein, calmodulin 1 Protein, calmodulin 2 Protein, calmodulin 1 (phosphorylase kinase, delta) L homeolog Protein, Calmodulin Protein, Calm1 Protein, Calm2 Protein, CALM1 Protein, calm1.L Protein, Cam Protein
    背景

    Background: Calmodulin (CaM) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the binding of Ca2+ is required for the activation of Calmodulin. Once bound to Ca2+, Calmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins such as kinases or phosphatases. Calmodulin is a small, highly conserved protein that is 148 amino acids long. The protein has two approximately symmetrical globular domains each containing a pair of EF-hand motifs (the N- and C-domain) separated by a flexible linker region for a total of four Ca2+ binding sites. Calmodulin mediates many crucial processes such as inflammation, metabolism, apoptosis, smooth muscle contraction, intracellular movement, short-term and long-term memory, and the immune response. Calmodulin is expressed in many cell types and can have different subcellular locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes, but it is always found intracellularly.

    Synonym: Calmodulin, CaM, CALM1, CALM, CAM, CAM1, CALM2, CAM2, CAMB, CALM3, CALML2, CAM3, CAMC, CAMIII

    分子量
    16.8 kDa
    UniProt
    P62158
    途径
    cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling
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