CD79a Protein (His tag)
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- 抗原 See all CD79a (CD79A) 蛋白
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This CD79a protein is labelled with His tag.
- 原理
- Recombinant Human CD79A(C-6His)
- 序列
- Leu33-Arg143
- 产品特性
- Recombinant Human CD79A is produced by our Mammalian expression system and the target gene encoding Leu33-Arg143 is expressed with a 6His tag at the C-terminus.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CD79A 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
- 别名
- CD79A (CD79A 产品)
- 别名
- CD79A Protein, Ig-alpha Protein, Iga Protein, Igalpha Protein, Ly-54 Protein, Ly54 Protein, mb-1 Protein, IGA Protein, MB-1 Protein, IG-alpha Protein, CD79a molecule Protein, CD79A antigen (immunoglobulin-associated alpha) Protein, Cd79a molecule-like Protein, CD79A Protein, Cd79a Protein, Cd79al Protein
- 背景
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Background: CD79A (also known as Mb-1, Ig alpha and B cell antigen receptor complex-associated protein alpha-chain) is a 30-40 kDa member of the Ig-Superfamily. Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Synonym: CD79A antigen, CD79a antigen, CD79A, MB1, MB-1
- 分子量
- 13.4 kDa
- UniProt
- P11912
- 途径
- BCR Signaling
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