AKR1C3 Protein (His tag)
-
- 抗原 See all AKR1C3 蛋白
- AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 人细胞
- 标记
- This AKR1C3 protein is labelled with His tag.
- 原理
- Recombinant Human AKR1C3 Protein (His Tag)
- 序列
- Met 1-Tyr323
- 产品特性
- Recombinant Human Aldo-Keto Reductase Family 1 Member C3 is produced by our Mammalian expression system and the target gene encoding Met1-Tyr323 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product AKR1C3 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
- 别名
- AKR1C3 (AKR1C3 产品)
- 别名
- AKR1C3 Protein, PGFS Protein, MGC134333 Protein, DD3 Protein, DDX Protein, HA1753 Protein, HAKRB Protein, HAKRe Protein, HSD17B5 Protein, hluPGFS Protein, Akr1c18 Protein, aldo-keto reductase family 1, member C3 L homeolog Protein, aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) Protein, aldo-keto reductase family 1 member C2 Protein, aldo-keto reductase family 1 member C3 Protein, aldo-keto reductase family 1, member C3 Protein, akr1c3.L Protein, AKR1C3 Protein, LOC722496 Protein, Akr1c3 Protein
- 背景
-
Background: AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols. It catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. It can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites.
Synonym: Aldo-Keto Reductase Family 1 Member C3, 17-Beta-Hydroxysteroid Dehydrogenase Type 5, 17-Beta-HSD 5, 3-Alpha-HSD Type II Brain, 3-Alpha-Hydroxysteroid Dehydrogenase Type 2, 3-Alpha-HSD Type 2, Chlordecone Reductase Homolog HAKRb, Dihydrodiol Dehydrogenase 3, DD-3, DD3, Dihydrodiol Dehydrogenase Type I, HA1753, Indanol Dehydrogenase, Prostaglandin F Synthase, Testosterone 17-Beta-Dehydrogenase 5, Trans-1,2-Dihydrobenzene-1,2-Diol Dehydrogenase, AKR1C3, DDH1, HSD17B5, KIAA0119, PGFS
- 分子量
- 37.8 kDa
- UniProt
- P42330
- 途径
- Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Protein targeting to Nucleus
-