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ALT Protein (His tag)

ALT 宿主: 大鼠 宿主: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7194188
发货至: 中国
  • 抗原 See all ALT 蛋白
    ALT (Alanine Aminotransferase (ALT))
    蛋白类型
    Recombinant
    宿主
    • 13
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    大鼠
    资源
    • 22
    • 5
    • 1
    • 1
    • 1
    Baculovirus infected Insect Cells
    标记
    This ALT protein is labelled with His tag.
    原理
    Recombinant Rat GPT1/GPT Protein (His Tag)
    序列
    Met 1-Ser 496
    产品特性
    A DNA sequence encoding the rat Gpt1 (NP_112301.1) (Met 1-Ser 496) with a C-terminal polyhistidine tag was expressed.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 10 % glycerol, 0.5 mM TCEP
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    ALT (Alanine Aminotransferase (ALT))
    别名
    GPT1/GPT (ALT 产品)
    别名
    AAT1 Protein, ALT1 Protein, GPT1 Protein, GPT Protein, Gpt1 Protein, An11g02620 Protein, AO090003000164 Protein, 233.t00009 Protein, 24.t00016 Protein, 1300007J06Rik Protein, 2310022B03Rik Protein, ALT Protein, Gpt-1 Protein, AU021132 Protein, Dpagt2 Protein, Gnpta Protein, gpt Protein, ALANINE AMINOTRANSFERAS Protein, AtAlaAT1 Protein, AtAlaATc Protein, T13M22.3 Protein, T13M22_3 Protein, alanine aminotransferas Protein, glutamic--pyruvic transaminase Protein, glutamic-pyruvate transaminase (alanine aminotransferase) Protein, alanine aminotransferase Protein, alanine aminotransferase 1 Protein, glutamic pyruvic transaminase, soluble Protein, dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) Protein, alanine aminotransferase 2-like Protein, Alanine aminotransferase 1, mitochondrial Protein, GPT Protein, Gpt Protein, Tb927.1.3950 Protein, ANI_1_368094 Protein, AOR_1_284154 Protein, ALAT_1 Protein, ALAAT1 Protein, EHI_159710 Protein, EHI_096750 Protein, LOC5572541 Protein, ALAT Protein, AAT2 Protein, Dpagt1 Protein, LOC100537633 Protein, AlaAT1 Protein
    背景

    Background: Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (GPT), is a pyridoxal enzyme which belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family, Alanine aminotransferase subfamily. Gpt / Gpt1 / ALT catalyses the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate, and plays a key role in the intermediary metabolism of glucose and amino acids. Gpt / Gpt1 / ALT is expressed in Liver, kidney, heart, and skeletal muscles and it expresses at moderate levels in the adipose tissue. As a key enzyme for gluconeogenesis, Gpt is a widely-used serum marker for liver injury. Two ALT isoenzymes have been identified, ALT1 and ALT2 (GPT1 and GPT2), which are encoded by separate genes and share significant sequence homology, but differ in their expression patterns. GPT1/GPT is widely distributed and mainly expressed in intestine, liver, fat tissues, colon, muscle, and heart, in the order of high to low expression level. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis.

    Synonym: Gpt1,Gpt,ALT1

    分子量
    55 kDa
    NCBI登录号
    NP_112301
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