Afamin Protein (AFM) (His tag)
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- 抗原 See all Afamin (AFM) 蛋白
- Afamin (AFM)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This Afamin protein is labelled with His tag.
- 原理
- Recombinant Human Afamin/AFM (C-6His)
- 序列
- Leu22-Asn599
- 产品特性
- Recombinant Human Afamin is produced by our Mammalian expression system and the target gene encoding Leu22-Asn599 is expressed with a 6His tag at the C-terminus.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product AFM 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Afamin (AFM)
- 别名
- Afamin/AFM (AFM 产品)
- 别名
- AFM Protein, ALB2 Protein, ALBA Protein, ALF Protein, Alf Protein, alpha-Alb Protein, afamin Protein, AFM Protein, Afm Protein
- 背景
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Background: Afamin also known as Alpha -Albumin is a secreted monomeric glycoprotein of the Alb/Albumin family of molecules. AFM is known to bind and transport vitamin E family molecules, playing an important role for transporting at the blood-brain-barrier. Afamin has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. AFM also serves as an osteoclast-derived chemoattractant for preosteoblasts, providing a rational for the observation that bone formation often follows bone resorption. The importance of Afamin in transport of molecules has led to a suggested diagnostic role in various diseases, including pre-eclampsia, ovarian cancer, and both gestational and type-2 diabetes.
Synonym: Afamin, AFM, ALB2, ALB2alpha-Alb, ALBA, ALBAalpha-albumin, ALF, Alpha-Alb, Alpha-albumin
- 分子量
- 67.6 kDa
- UniProt
- P43652
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