ADAM15 Protein (His tag)
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- 抗原 See all ADAM15 蛋白
- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This ADAM15 protein is labelled with His tag.
- 原理
- Recombinant Mouse ADAM15 Protein (His Tag)(Active)
- 序列
- Met 1-Thr 697
- 产品特性
- A DNA sequence encoding the mouse ADAM15 (O88839-1) extracellular domain (Met 1-Thr 697) was expressed, with a C-terminal polyhistidine tag.
- 纯度
- > 90 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- 1. Measured by its ability to bind human PTK6 in a functional ELISA.2. Measured by its ability to bind human SRC in a functional ELISA.3. Measured by its ability to bind mouse SRC in a functional ELISA. 4. Measured by its ability to bind human LYN in a functional ELISA.
- Top Product
- Discover our top product ADAM15 蛋白
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ADAM Metallopeptidase Domain 15 (ADAM15) (AA 1-772) protein (GST tag)
ADAM15 宿主: 人 宿主: 小麦胚 Recombinant ELISA, AP, AA, WB
ADAM Metallopeptidase Domain 15 (ADAM15) (AA 301-410) protein (GST tag)ADAM15 宿主: 人 宿主: 小麦胚 Recombinant ELISA, AP, AA, WB
ADAM Metallopeptidase Domain 15 (ADAM15) (AA 18-696) protein (Fc Tag)ADAM15 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ADAM Metallopeptidase Domain 15 (ADAM15) (AA 207-452), (Extracellular) protein (GST tag)ADAM15 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
- 别名
- ADAM15 (ADAM15 产品)
- 别名
- ADAM15 Protein, mdc15 Protein, MDC15 Protein, metargidin Protein, tMDCVI Protein, ADAM metallopeptidase domain 15 Protein, ADAM metallopeptidase domain 15 L homeolog Protein, a disintegrin and metallopeptidase domain 15 (metargidin) Protein, ADAM15 Protein, adam15.L Protein, adam15 Protein, Adam15 Protein
- 背景
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Background: ADAM15, also known as Metargidin, is a type I transmembrane glycoprotein belonging to the ADAM (A Disintegrin and Metalloprotease Domain) family of proteins and is widely expressed in different tissues and cell types. Members of this family contain an amino-terminal metalloprotease domain followed by a disintegrin domain, a cysteine-rich region and a membrane proximal EGF-like domain. The disintegrin domain of ADAM15/metargidin contains an RGD tripeptide sequence, suggesting that it may potentially interact with the integrin family of proteins. ADAM15 is a transmembrane multi-domain proteins implicated in proteolysis, cell-cell and cell-matrix interactions in various disease conditions. There is also evidence supporting a role for ADAM15 in angiogenesis and angioinvasion of tumor cells, which are critical for unrestrained tumor growth and metastatic spread. Given its diverse functions, ADAM15 may represent a pivotal regulatory component of tumor progression, an important target for therapeutic intervention, or emerge as a biomarker of disease progression.
Synonym: MDC15,metargidin
- 分子量
- 74.6 kDa
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