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HPD Protein (His tag)

HPD 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318119
发货至: 中国
  • 抗原 See all HPD 蛋白
    HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    资源
    • 8
    • 5
    • 1
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    大肠杆菌(E. Coli)
    标记
    This HPD protein is labelled with His tag.
    原理
    Recombinant Human HPD/4HPPD Protein (His Tag)
    序列
    Met 1-Met393
    产品特性
    Recombinant Human 4-Hydroxyphenylpyruvate Dioxygenase is produced by our E.coli expression system and the target gene encoding Met1-Met393 is expressed with a 6His tag at the N-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product HPD 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 50 mM NaCl, 1 mM DTT, 0.1 mM PMSF, pH 8.0.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))
    别名
    HPD/4HPPD (HPD 产品)
    背景

    Background: 4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) belongs to the 4HPPD family. 4HPPD is a key enzyme in the degradation of tyrosine, which catalyzes the second reaction in the catabolism of tyrosine the conversation of 4-hydroxyphenylpyruvate to homogentisate. 4HPPD exists in homodimer forms, which uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. When the active 4HPPD enzyme concentration is low in the human body, it results in high levels of tyrosine concentration in the blood, which can cause mild mental retardation at birth, and degradation in vision as a patient grows older.

    Synonym: 4-Hydroxyphenylpyruvate Dioxygenase, 4-Hydroxyphenylpyruvic Acid Oxidase, 4HPPD, HPD, HPPDase, HPD, PPD

    分子量
    47.1 kDa
    UniProt
    P32754
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