CCR5 Protein-VLP
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- 抗原 See all CCR5 蛋白
- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
- 蛋白类型
- VLP
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human CCR5 Full Length Protein-VLP (HEK293)
- 序列
- Met 1 - Leu 352
- 产品特性
- Human CCR5 Full Length Protein-VLP (CC5-H52P3) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Leu 352 (Accession # P51681-1).
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product CCR5 蛋白
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- 应用备注
- The protein has a calculated MW of 40.5 kDa.
- 说明
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Virus-like particles (VLPs) are formed by self-assembly of envelop/capsid proteins from viruses. Membrance Proteins can be constituted in-situ with VLPs produced from HEK293 cell cultures. These VLPs concentrate conformationally intact membrane proteins directly on the cell surface and produce soluble, high-concentration proteins perfect for immunization and antibody screening.
The VLPs provide the display of properly folded membrane proteins in their native cellular membrane in a compact size of 100~300 nm diameter (similar to the size of most viruses) making it optimal targets for dendritic cells in vivo and surface attachment for phage display. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -80 °C
- 储存方法
- -70°C
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- 抗原
- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
- 别名
- CCR5 (CCR5 产品)
- 别名
- CC-CKR-5 Protein, CCCKR5 Protein, CCR-5 Protein, CD195 Protein, CKR-5 Protein, CKR5 Protein, CMKBR5 Protein, IDDM22 Protein, Ckr5 Protein, Cmkbr5 Protein, CCR1-L Protein, GPCR Protein, CCR5 Protein, AM4-7 Protein, C-C motif chemokine receptor 5 (gene/pseudogene) Protein, chemokine (C-C motif) receptor 5 Protein, C-C motif chemokine receptor 5 Protein, CCR5 Protein, Ccr5 Protein
- 背景
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Synonyms: CCR5,CMKBR5,CD195,CC-CKR-5,CHEMR13,
Description: Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.5 Publications (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1. - 分子量
- 40.5 kDa
- 途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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