E-cadherin Protein (AA 23-706) (Fc Tag)
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- 抗原 See all E-cadherin (CDH1) 蛋白
- E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 23-706
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This E-cadherin protein is labelled with Fc Tag.
- 原理
- Recombinant Human CDH1 with C-terminal human Fc tag
- 特异性
- CDH1 (Glu23-Gln706) hFc (Glu99-Ala330)
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CDH1 蛋白
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Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 1-882) protein (GST tag)
CDH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 381-480) protein (GST tag)CDH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 155-707) protein (His tag)CDH1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) protein (Fc Tag)CDH1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 75 % as determined by SDS-PAGE
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (Active) protein (His tag)CDH1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 23-621) (Active) protein (Fc Tag)CDH1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
- 别名
- CDH1 (CDH1 产品)
- 别名
- Arc-1 Protein, CD324 Protein, CDHE Protein, ECAD Protein, LCAM Protein, UVO Protein, E-cadherin Protein, cdh1 Protein, si:dz180o5.2 Protein, uvo Protein, lcam Protein, E-Cad Protein, XBcad Protein, l-cam Protein, xcdh1 Protein, cdhc-A Protein, xb-cad Protein, XTCAD-1 Protein, c-cadherin Protein, cadherin-1 Protein, uvomorulin Protein, XB-cadherin Protein, arc-1 Protein, cd324 Protein, cdhe Protein, ecad Protein, AA960649 Protein, E-cad Protein, Ecad Protein, L-CAM Protein, Um Protein, cadherin 1 Protein, si:busm1-180o5.2 Protein, cadherin 1, type 1, E-cadherin (epithelial) Protein, cadherin 1, type 1 S homeolog Protein, CDH1 Protein, si:busm1-180o5.2 Protein, cdh1 Protein, Cdh1 Protein, cdh1.S Protein
- 背景
- This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]
- 分子量
- predicted molecular mass of 101.6 kDa after removal of the signal peptide. The apparent molecular mass of CDH1-hFc is 100-130 kDa due to glycosylation.
- UniProt
- P12830
- 途径
- WNT signaling, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation
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