Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
储存条件
-20 °C,-80 °C
储存方法
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
BDPLT11 Protein, GPIV Protein, GPVI Protein, 9830166G18Rik Protein, Gm469 Protein, Gpvi Protein, GP6 Protein, glycoprotein VI platelet Protein, glycoprotein 6 (platelet) Protein, glycoprotein VI Protein, platelet glycoprotein VI Protein, GP6 Protein, Gp6 Protein, LOC103346235 Protein
背景
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
分子量
predicted molecular mass of 53.1 kDa after removal of the signal peptide. The apparent molecular mass of GP6-hFc is 55-100 kDa due to glycosylation.