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PCSK9 Protein (AA 31-692) (Fc Tag)

PCSK9 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7092725
发货至: 中国
  • 抗原 See all PCSK9 蛋白
    PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))
    蛋白类型
    Recombinant
    产品特性
    AA 31-692
    宿主
    • 17
    • 10
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    资源
    • 25
    • 7
    • 6
    • 1
    • 1
    HEK-293 Cells
    标记
    This PCSK9 protein is labelled with Fc Tag.
    原理
    Recombinant Human PCSK9 Protein with C-terminal human Fc tag
    特异性
    PCSK9 (Ser31-Gln692) hFc (Glu99-Ala330)
    产品特性
    Extracellular Domain Protein
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product PCSK9 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))
    别名
    PCSK9 (PCSK9 产品)
    别名
    FH3 Protein, HCHOLA3 Protein, LDLCQ1 Protein, NARC-1 Protein, NARC1 Protein, PC9 Protein, AI415265 Protein, AI747682 Protein, Narc1 Protein, proprotein convertase subtilisin/kexin type 9 Protein, proprotein convertase subtilisin/kexin type 9 L homeolog Protein, PCSK9 Protein, pcsk9.L Protein, pcsk9 Protein, Pcsk9 Protein
    背景
    This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants.
    分子量
    predicted molecular mass of 97.2 kDa after removal of the signal peptide.The apparent molecular mass of PCSK9-hFc is 100-130 kDa due to glycosylation.
    UniProt
    Q8NBP7
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