YAP1 Protein (AA 1-504) (His tag)
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- 抗原 See all YAP1 蛋白
- YAP1 (Yes-Associated Protein 1 (YAP1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-504
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This YAP1 protein is labelled with His tag.
- 原理
- Recombinant human YAP1 protein with C-terminal 6xHis tag
- 特异性
- YAP1 (Met1-Leu504) 6xHis tag
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product YAP1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- YAP1 (Yes-Associated Protein 1 (YAP1))
- 别名
- YAP1 (YAP1 产品)
- 别名
- YAP Protein, YAP2 Protein, YAP65 Protein, YKI Protein, xyap Protein, yap Protein, yap2 Protein, yap65 Protein, yki Protein, AI325207 Protein, Yap Protein, Yap65 Protein, Yki Protein, Yorkie Protein, cb194 Protein, sb:cb194 Protein, si:ch211-181p1.5 Protein, si:dkey-3b8.3 Protein, wu:fc18c04 Protein, zgc:158380 Protein, Yes associated protein 1 Protein, Yes associated protein 1 S homeolog Protein, yes-associated protein 1 Protein, Yes-associated protein 1 Protein, YAP1 Protein, yap1.S Protein, Yap1 Protein, yap1 Protein
- 背景
- This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
- 分子量
- predicted molecular mass of 55.3 kDa after removal of the signal peptide.
- 基因ID
- 10413
- UniProt
- P46937
- 途径
- MAPK Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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